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Robert Fram Selected Research

VX-944

9/2005Novel inosine monophosphate dehydrogenase inhibitor VX-944 induces apoptosis in multiple myeloma cells primarily via caspase-independent AIF/Endo G pathway.

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Robert Fram Research Topics

Disease

2Multiple Myeloma
09/2005 - 07/2005
2Neoplasms (Cancer)
07/2005 - 02/2002
1Severe Combined Immunodeficiency (Bare Lymphocyte Syndrome)
07/2005

Drug/Important Bio-Agent (IBA)

1Oxidoreductases (Dehydrogenase)IBA
09/2005
1VX-944IBA
09/2005
1Inosine Monophosphate (IMP)IBA
09/2005
1CaspasesIBA
09/2005
1Interleukin-6 (Interleukin 6)IBA
07/2005
1Interleukin-6 Receptors (Interleukin 6 Receptor)IBA
07/2005

Therapy/Procedure

1Therapeutics
02/2002